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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK1
All Species:
26.97
Human Site:
S248
Identified Species:
49.44
UniProt:
Q96PY6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PY6
NP_036356.1
1258
142828
S248
R
N
P
R
D
R
P
S
V
N
S
I
L
E
K
Chimpanzee
Pan troglodytes
XP_001153129
1258
142786
S248
R
N
P
R
D
R
P
S
V
N
S
I
L
E
K
Rhesus Macaque
Macaca mulatta
XP_001082793
1258
142958
S248
R
N
P
R
D
R
P
S
V
N
S
I
L
E
K
Dog
Lupus familis
XP_543184
1286
146207
S248
R
N
P
R
D
R
P
S
V
N
S
I
L
E
K
Cat
Felis silvestris
Mouse
Mus musculus
P51954
1203
136672
S248
R
N
P
R
D
R
P
S
V
N
S
I
L
E
K
Rat
Rattus norvegicus
NP_001099552
648
74414
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513277
864
98961
Chicken
Gallus gallus
XP_420401
1281
145243
S248
R
N
P
R
D
R
P
S
V
N
S
I
L
E
K
Frog
Xenopus laevis
Q7ZZC8
944
104521
R76
R
L
S
E
K
E
R
R
D
A
L
N
E
I
V
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782796
1091
120115
S219
R
S
A
R
D
R
P
S
I
N
S
V
L
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9CAU7
606
68016
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48479
858
94329
Conservation
Percent
Protein Identity:
100
99.6
97.5
85
N.A.
79.2
45.9
N.A.
30.2
66.2
22.4
22.7
N.A.
N.A.
N.A.
N.A.
32.9
Protein Similarity:
100
99.7
98.4
90.8
N.A.
85.6
48.5
N.A.
44.3
78
39.2
34.4
N.A.
N.A.
N.A.
N.A.
48.5
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
0
100
6.6
0
N.A.
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
0
100
6.6
0
N.A.
N.A.
N.A.
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
20.1
Protein Similarity:
N.A.
N.A.
N.A.
33.7
N.A.
35.1
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
54
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
8
0
8
0
0
0
0
0
0
8
47
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
47
0
8
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
54
% K
% Leu:
0
8
0
0
0
0
0
0
0
0
8
0
54
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
47
0
0
0
0
0
0
0
54
0
8
0
0
0
% N
% Pro:
0
0
47
0
0
0
54
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
62
0
0
54
0
54
8
8
0
0
0
0
0
0
0
% R
% Ser:
0
8
8
0
0
0
0
54
0
0
54
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
47
0
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _